Glutathione Reductase antibody (C-Term)

Catalog No. ABIN655985

The Rabbit Polyclonal anti-Glutathione Reductase antibody is suitable to detect Glutathione Reductase in samples from Human. It has been validated for WB, IF, FACS and IHC (p).

Quick Overview for Glutathione Reductase antibody (C-Term) (ABIN655985)

Target: Glutathione Reductase (GSR)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Glutathione Reductase antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB31981

Product Details anti-Glutathione Reductase Antibody

Binding Specificity: AA 380-408, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This GSR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 380-408 amino acids from the C-terminal region of human GSR.

Isotype: IgG

Application Details

Application Notes: IF: 1:10~50. WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for Glutathione Reductase

Target: Glutathione Reductase (GSR)

Alternative Name: GSR

Background: This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein. It is a central enzyme of cellular antioxidant defense, and reduces oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH, which is an important cellular antioxidant. Rare mutations in this gene result in hereditary glutathione reductase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been found.

Molecular Weight: 56257

Gene ID: 2936

NCBI Accession: NP_000628, NP_001182031, NP_001182032, NP_001182033

UniProt: P00390

Pathways: Thyroid Hormone Synthesis, Cell RedoxHomeostasis