Indian Hedgehog antibody (AA 202-411)

Catalog No. ABIN6142275

This Rabbit Polyclonal antibody specifically detects Indian Hedgehog in WB. It exhibits reactivity toward Human.

Quick Overview for Indian Hedgehog antibody (AA 202-411) (ABIN6142275)

Target: Indian Hedgehog (IHH)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Indian Hedgehog antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Indian Hedgehog Antibody

Binding Specificity: AA 202-411

Sequence: GCFPAGAQVR LESGARVALS AVRPGDRVLA MGEDGSPTFS DVLIFLDREP HRLRAFQVIE TQDPPRRLAL TPAHLLFTAD NHTEPAARFR ATFASHVQPG QYVLVAGVPG LQPARVAAVS THVALGAYAP LTKHGTLVVE DVVASCFAAV ADHHLAQLAF WPLRLFHSLA WGSWTPGEGV HWYPQLLYRL GRLLLEEGSF HPLGMSGAGS

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 202-411 of human IHH (NP_002172.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Indian Hedgehog

Target: Indian Hedgehog (IHH)

Alternative Name: IHH

Background: This gene encodes a member of the hedgehog family of proteins. The encoded preproprotein is proteolytically processed to generate multiple protein products, including an N-terminal fragment that is involved in signaling. Hedgehog family proteins are essential secreted signaling molecules that regulate a variety of developmental processes including growth, patterning and morphogenesis. The protein encoded by this gene specifically plays a role in bone growth and differentiation. Mutations in this gene are the cause of brachydactyly type A1, which is characterized by shortening or malformation of the fingers and toes. Mutations in this gene are also the cause of acrocapitofemoral dysplasia.,IHH,BDA1,HHG2,Cell Biology & Developmental Biology,Hedgehog Signaling Pathway,Stem Cells,IHH

Molecular Weight: 45 kDa

Gene ID: 3549

UniProt: Q14623

Pathways: Hedgehog Signaling