IKAP/p150 antibody (AA 1093-1332)

Catalog No. ABIN6142278

The Rabbit Polyclonal anti-IKAP/p150 antibody has been validated for WB and IHC. It is suitable to detect IKAP/p150 in samples from Human.

Quick Overview for IKAP/p150 antibody (AA 1093-1332) (ABIN6142278)

Target: IKAP/p150 (ELP1) (Elongator Complex Protein 1 (ELP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IKAP/p150 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-IKAP/p150 Antibody

Binding Specificity: AA 1093-1332

Sequence: LRLVYKYNRL DIIETNVKPS ILEAQKNYMA FLDSQTATFS RHKKRLLVVR ELKEQAQQAG LDDEVPHGQE SDLFSETSSV VSGSEMSGKY SHSNSRISAR SSKNRRKAER KKHSLKEGSP LEDLALLEAL SEVVQNTENL KDEVYHILKV LFLFEFDEQG RELQKAFEDT LQLMERSLPE IWTLTYQQNS ATPVLGPNST ANSIMASYQQ QKTSVPVLDA ELFIPPKINR RTQWKLSLLD

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1093-1332 of human IKBKAP (NP_003631.2).

Isotype: IgG

Application Details

Application Notes: WB,1:1000 - 1:4000,IHC,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for IKAP/p150

Target: IKAP/p150 (ELP1) (Elongator Complex Protein 1 (ELP1))

Alternative Name: IKBKAP

Background: The protein encoded by this gene is a scaffold protein and a regulator for three different kinases involved in proinflammatory signaling. The encoded protein can bind NF-kappa-B-inducing kinase and I-kappa-B kinases through separate domains and assemble them into an active kinase complex. Mutations in this gene have been associated with familial dysautonomia. Alternative splicing results in multiple transcript variants encoding different isoforms.,IKBKAP,DYS,ELP1,FD,IKAP,IKI3,TOT1,Epigenetics & Nuclear Signaling,Signal Transduction,IKBKAP

Molecular Weight: 150 kDa

Gene ID: 8518

UniProt: O95163