IL11RA antibody (AA 30-290)

Catalog No. ABIN6142294

The Rabbit Polyclonal anti-IL11RA antibody has been validated for WB. It is suitable to detect IL11RA in samples from Human.

Quick Overview for IL11RA antibody (AA 30-290) (ABIN6142294)

Target: IL11RA (Interleukin 11 Receptor, alpha (IL11RA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL11RA antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-IL11RA Antibody

Binding Specificity: AA 30-290

Sequence: WGPPGVQYGQ PGRSVKLCCP GVTAGDPVSW FRDGEPKLLQ GPDSGLGHEL VLAQADSTDE GTYICQTLDG ALGGTVTLQL GYPPARPVVS CQAADYENFS CTWSPSQISG LPTRYLTSYR KKTVLGADSQ RRSPSTGPWP CPQDPLGAAR CVVHGAEFWS QYRINVTEVN PLGASTRLLD VSLQSILRPD PPQGLRVESV PGYPRRLRAS WTYPASWPCQ PHFLLKFRLQ YRPAQHPAWS TVEPAGLEEV ITDAVAGLPH A

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 30-290 of human IL11RA (NP_001136256.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for IL11RA

Target: IL11RA (Interleukin 11 Receptor, alpha (IL11RA))

Alternative Name: IL11RA

Background: Interleukin 11 is a stromal cell-derived cytokine that belongs to a family of pleiotropic and redundant cytokines that use the gp130 transducing subunit in their high affinity receptors. This gene encodes the IL-11 receptor, which is a member of the hematopoietic cytokine receptor family. This particular receptor is very similar to ciliary neurotrophic factor, since both contain an extracellular region with a 2-domain structure composed of an immunoglobulin-like domain and a cytokine receptor-like domain. Multiple alternatively spliced transcript variants have been found for this gene.,IL11RA,CRSDA,Cancer,Tumor biomarkers,Immunology & Inflammation,Cytokines,Interleukins,Cell Intrinsic Innate Immunity Signaling Pathway,Stem Cells,Hematopoietic Progenitors,IL11RA

Molecular Weight: 41 kDa/45 kDa

Gene ID: 3590

UniProt: Q14626

Pathways: JAK-STAT Signaling, Growth Factor Binding