IMPDH1 antibody (AA 434-563)

Catalog No. ABIN6142433

The Rabbit Polyclonal anti-IMPDH1 antibody has been validated for WB and IF. It is suitable to detect IMPDH1 in samples from Human.

Quick Overview for IMPDH1 antibody (AA 434-563) (ABIN6142433)

Target: IMPDH1 (Inosine 5'-Phosphate Dehydrogenase 1 (IMPDH1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IMPDH1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-IMPDH1 Antibody

Binding Specificity: AA 434-563

Sequence: MMGSLLAATT EAPGEYFFSD GVRLKKYRGM GSLDAMEKSS SSQKRYFSEG DKVKIAQGVS GSIQDKGSIQ KFVPYLIAGI QHGCQDIGAR SLSVLRSMMY SGELKFEKRT MSAQIEGGVH GLHSYEKRLY

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 434-563 of human IMPDH1 (NP_899066.1).

Isotype: IgG

Application Details

Application Notes: WB,1:1000 - 1:2000,IF,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for IMPDH1

Target: IMPDH1 (Inosine 5'-Phosphate Dehydrogenase 1 (IMPDH1))

Alternative Name: IMPDH1

Background: The protein encoded by this gene acts as a homotetramer to regulate cell growth. The encoded protein is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10). Several transcript variants encoding different isoforms have been found for this gene.,IMPDH1,IMPD,IMPD1,IMPDH-I,LCA11,RP10,sWSS2608,Epigenetics & Nuclear Signaling,Cancer,Signal Transduction,Endocrine & Metabolism,Nucleotide metabolism,Neuroscience,IMPDH1

Molecular Weight: 52 kDa/54 kDa/55 kDa/60 kDa/63 kDa/64 kDa

Gene ID: 3614

UniProt: P20839

Pathways: Ribonucleoside Biosynthetic Process