IRAK1 antibody (AA 424-633)

Catalog No. ABIN6142514

This Rabbit Polyclonal antibody specifically detects IRAK1 in WB and IF. It exhibits reactivity toward Human.

Quick Overview for IRAK1 antibody (AA 424-633) (ABIN6142514)

Target: IRAK1 (Interleukin-1 Receptor-Associated Kinase 1 (IRAK1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IRAK1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-IRAK1 Antibody

Binding Specificity: AA 424-633

Sequence: VKTHGARTKY LVYERLEKLQ AVVAGVPGHS EAASCIPPSP QENSYVSSTG RAHSGAAPWQ PLAAPSGASA QAAEQLQRGP NQPVESDESL GGLSAALRSW HLTPSCPLDP APLREAGCPQ GDTAGESSWG SGPGSRPTAV EGLALGSSAS SSSEPPQIII NPARQKMVQK LALYEDGALD SLQLLSSSSL PGLGLEQDRQ GPEESDEFQS

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 424-633 of human IRAK1 (NP_001020414.1).

Isotype: IgG

Application Details

Application Notes: WB,1:1000 - 1:3000,IF,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for IRAK1

Target: IRAK1 (Interleukin-1 Receptor-Associated Kinase 1 (IRAK1))

Alternative Name: IRAK1

Background: This gene encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This gene is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,IRAK1,IRAK,pelle,Signal Transduction,Kinase,Serine/threonine kinases,Immunology & Inflammation,Cytokines,Interleukins,NF-kB Signaling Pathway,Toll-like Receptor Signaling Pathway,Cell Intrinsic Innate Immunity Signaling Pathway,TLR Signaling,Cardiovascular,IRAK1

Molecular Weight: 68 kDa/73 kDa/74 kDa/76 kDa

Gene ID: 3654

UniProt: P51617

Pathways: NF-kappaB Signaling, TLR Signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades