ISY1 antibody (AA 1-307)

Catalog No. ABIN6142553

The Rabbit Polyclonal anti-ISY1 antibody is suitable to detect ISY1 in samples from Human. It has been validated for WB.

Quick Overview for ISY1 antibody (AA 1-307) (ABIN6142553)

Target: ISY1 (ISY1 Splicing Factor Homolog (ISY1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ISY1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ISY1 Antibody

Binding Specificity: AA 1-307

Sequence: MARNAEKAMT ALARFRQAQL EEGKVKERRP FLASECTELP KAEKWRRQII GEISKKVAQI QNAGLGEFRI RDLNDEINKL LREKGHWEVR IKELGGPDYG KVGPKMLDHE GKEVPGNRGY KYFGAAKDLP GVRELFEKER QVRWLMPVIP ALWEAEAGGS QALPPPRKTR AELMKAIDFE YYGYLDEDDG VIVPLEQEYE KKLRAELVEK WKAEREARLA RGEKEEEEEE EEEINIYAVT EEESDEEGSQ EKGGDDSQQK FIAHVPVPSQ QEIEEALVRR KKMELLQKYA SETLQAQSEE ARRLLGY

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-307 of human ISY1 (NP_001186398.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ISY1

Target: ISY1 (ISY1 Splicing Factor Homolog (ISY1))

Alternative Name: ISY1

Background: Component of the spliceosome C complex required for the selective processing of microRNAs during embryonic stem cell differentiation (By similarity. Required for the biogenesis of all miRNAs from the pri-miR-17-92 primary transcript except miR-92a (By similarity. Only required for the biogenesis of miR-290 and miR-96 from the pri-miR-290-295 and pri-miR-96-183 primary transcripts, respectively (By similarity. Required during the transition of embryonic stem cells (ESCs from the naive to primed state (By similarity. By enhancing miRNA biogenesis, promotes exit of ESCs from the naive state to an intermediate state of poised pluripotency, which precedes transition to the primed state (By similarity. Involved in pre-mRNA splicing as component of the spliceosome.,ISY1,FSAP33,Epigenetics & Nuclear Signaling,RNA Binding,ISY1

Molecular Weight: 32 kDa/35 kDa/37 kDa

Gene ID: 57461

UniProt: Q9ULR0