ITGA5 antibody (AA 750-1000)

Catalog No. ABIN6142564

This anti-ITGA5 antibody is a Rabbit Polyclonal antibody detecting ITGA5 in WB and IF. Suitable for Human.

Quick Overview for ITGA5 antibody (AA 750-1000) (ABIN6142564)

Target: ITGA5 (Integrin, alpha 5 (ITGA5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ITGA5 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-ITGA5 Antibody

Binding Specificity: AA 750-1000

Sequence: TVPHLRDTKK TIQFDFQILS KNLNNSQSDV VSFRLSVEAQ AQVTLNGVSK PEAVLFPVSD WHPRDQPQKE EDLGPAVHHV YELINQGPSS ISQGVLELSC PQALEGQQLL YVTRVTGLNC TTNHPINPKG LELDPEGSLH HQQKREAPSR SSASSGPQIL KCPEAECFRL RCELGPLHQQ ESQSLQLHFR VWAKTFLQRE HQPFSLQCEA VYKALKMPYR ILPRQLPQKE RQVATAVQWT KAEGSYGVPL W

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 750-1000 of human Integrin alpha 5 (ITGA5/CD49e) (NP_002196.4).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ITGA5

Target: ITGA5 (Integrin, alpha 5 (ITGA5))

Alternative Name: ITGA5

Background: The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 5 subunit. This subunit associates with the beta 1 subunit to form a fibronectin receptor. This integrin may promote tumor invasion, and higher expression of this gene may be correlated with shorter survival time in lung cancer patients. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes.,CD49e,FNRA,VLA-5,VLA5A,Integrin alpha 5,ITGA5,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,PI3K-Akt Signaling Pathway,MAPK-Erk Signaling Pathway,Cell Biology & Developmental Biology,Cell Adhesion,Cytoskeleton,Immunology & Inflammation,CD markers,Stem Cells,Endothelial Progenitors,Hematopoietic Progenitors,ITGA5

Molecular Weight: 114 kDa

Gene ID: 3678

UniProt: P08648

Pathways: Integrin Complex