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ITGA8 antibody (AA 907-1000)

ITGA8 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6142568
  • Target See all ITGA8 Antibodies
    ITGA8 (Integrin alpha-8 (ITGA8))
    Binding Specificity
    • 10
    • 8
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 907-1000
    Reactivity
    • 37
    • 10
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 32
    • 5
    • 4
    Rabbit
    Clonality
    • 37
    • 4
    Polyclonal
    Conjugate
    • 18
    • 5
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ITGA8 antibody is un-conjugated
    Application
    • 28
    • 22
    • 16
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    DVHVVEFHRQ SPAKILNCTN IECLQISCAV GRLEGGESAV LKVRSRLWAH TFLQRKNDPY ALASLVSFEV KKMPYTDQPA KLPEGSIVIK TSVI
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Polyclonal Antibodies
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 907-1000 of human ITGA8 (NP_003629.2).
    Isotype
    IgG
    Top Product
    Discover our top product ITGA8 Primary Antibody
  • Application Notes
    WB,1:500 - 1:2000
    Comment

    HIGH QUALITY

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    ITGA8 (Integrin alpha-8 (ITGA8))
    Alternative Name
    ITGA8 (ITGA8 Products)
    Synonyms
    AI447669 antibody, RGD1564327 antibody, integrin alpha 8 antibody, integrin subunit alpha 8 antibody, Itga8 antibody, ITGA8 antibody
    Background
    Integrins are heterodimeric transmembrane receptor proteins that mediate numerous cellular processes including cell adhesion, cytoskeletal rearrangement, and activation of cell signaling pathways. Integrins are composed of alpha and beta subunits. This gene encodes the alpha 8 subunit of the heterodimeric integrin alpha8beta1 protein. The encoded protein is a single-pass type 1 membrane protein that contains multiple FG-GAP repeats. This repeat is predicted to fold into a beta propeller structure. This gene regulates the recruitment of mesenchymal cells into epithelial structures, mediates cell-cell interactions, and regulates neurite outgrowth of sensory and motor neurons. The integrin alpha8beta1 protein thus plays an important role in wound-healing and organogenesis. Mutations in this gene have been associated with renal hypodysplasia/aplasia-1 (RHDA1) and with several animal models of chronic kidney disease. Alternate splicing results in multiple transcript variants encoding distinct isoforms.,ITGA8,Signal Transduction,PI3K-Akt Signaling Pathway,MAPK-Erk Signaling Pathway,Cell Biology & Developmental Biology,Cell Adhesion,Cytoskeleton,ITGA8
    Molecular Weight
    117 kDa
    Gene ID
    8516
    UniProt
    P53708
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