KLF17 antibody (AA 210-389)
Quick Overview for KLF17 antibody (AA 210-389) (ABIN6142915)
Target
See all KLF17 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 210-389
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Sequence
- QMLPPQDAHD LGMPPAESQS LLVLGSQDSL VSQPDSQEGP FLPEQPGPAP QTVEKNSRPQ EGTGRRGSSE ARPYCCNYEN CGKAYTKRSH LVSHQRKHTG ERPYSCNWES CSWSFFRSDE LRRHMRVHTR YRPYKCDQCS REFMRSDHLK QHQKTHRPGP SDPQANNNNG EQDSPPAAGP
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Cross-Reactivity
- Human, Mouse
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Characteristics
- Polyclonal Antibodies
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 210-389 of human KLF17 (NP_775755.3).
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Isotype
- IgG
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Application Notes
- WB,1:500 - 1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- KLF17 (Kruppel-Like Factor 17 (KLF17))
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Alternative Name
- KLF17
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Background
- Transcription repressor that binds to the promoter of target genes and prevents their expression. Acts as a negative regulator of epithelial-mesenchymal transition and metastasis in breast cancer. Specifically binds the 5'-CACCC-3' sequence in the promoter of ID1, a key metastasis regulator in breast cancer, and repress its expression. May be a germ cell-specific transcription factor that plays important roles in spermatid differentiation and oocyte development (By similarity.,KLF17,ZNF393,Zfp393,Epigenetics & Nuclear Signaling,Transcription Factors,KLF17
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Molecular Weight
- 42 kDa
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Gene ID
- 128209
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UniProt
- Q5JT82
Target
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