KLKB1 antibody (AA 20-300)

Catalog No. ABIN6142966

This anti-KLKB1 antibody is a Rabbit Polyclonal antibody detecting KLKB1 in WB and IHC. Suitable for Human.

Quick Overview for KLKB1 antibody (AA 20-300) (ABIN6142966)

Target: KLKB1 (Kallikrein B, Plasma (Fletcher Factor) 1 (KLKB1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KLKB1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-KLKB1 Antibody

Binding Specificity: AA 20-300

Sequence: GCLTQLYENA FFRGGDVASM YTPNAQYCQM RCTFHPRCLL FSFLPASSIN DMEKRFGCFL KDSVTGTLPK VHRTGAVSGH SLKQCGHQIS ACHRDIYKGV DMRGVNFNVS KVSSVEECQK RCTSNIRCQF FSYATQTFHK AEYRNNCLLK YSPGGTPTAI KVLSNVESGF SLKPCALSEI GCHMNIFQHL AFSDVDVARV LTPDAFVCRT ICTYHPNCLF FTFYTNVWKI ESQRNVCLLK TSESGTPSSS TPQENTISGY SLLTCKRTLP EPCHSKIYPG V

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 20-300 of human KLKB1 (NP_000883.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for KLKB1

Target: KLKB1 (Kallikrein B, Plasma (Fletcher Factor) 1 (KLKB1))

Alternative Name: KLKB1

Background: This gene encodes a glycoprotein that participates in the surface-dependent activation of blood coagulation, fibrinolysis, kinin generation and inflammation. The encoded preproprotein present in plasma as a non-covalent complex with high molecular weight kininogen undergoes proteolytic processing mediated by activated coagulation factor XII to generate a disulfide-linked, heterodimeric serine protease comprised of heavy and light chains. Certain mutations in this gene cause prekallikrein deficiency. Alternative splicing results in multiple transcript variants encoding different isoforms.,KLKB1,KLK3,PKK,PKKD,PPK,Cell Biology & Developmental Biology,Ubiquitin,KLKB1

Molecular Weight: 71 kDa

Gene ID: 3818

UniProt: P03952

Pathways: Complement System, Brown Fat Cell Differentiation