LLGL2 antibody (AA 900-1000)
Quick Overview for LLGL2 antibody (AA 900-1000) (ABIN6143260)
Target
See all LLGL2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 900-1000
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Sequence
- IASCVFTKYG QGFYLISPSE FERFSLSTKW LVEPRCLVDS TKAKKHNRPS NGNGTGLKMT SSGHVRNSKS QSDGDEKKPG PVMEHALLND AWVLKEIQST L
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Cross-Reactivity
- Mouse, Rat
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Characteristics
- Polyclonal Antibodies
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Immunogen
- A synthetic peptide corresponding to a sequence within amino acids 900-1000 of mouse LLGL2 (NP_663413.2).
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Isotype
- IgG
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Application Notes
- WB,1:500 - 1:2000,IHC,1:50 - 1:100
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- LLGL2 (Lethal Giant Larvae Homolog 2 (LLGL2))
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Alternative Name
- LLGL2
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Background
- The lethal (2) giant larvae protein of Drosophila plays a role in asymmetric cell division, epithelial cell polarity, and cell migration. This human gene encodes a protein similar to lethal (2) giant larvae of Drosophila. In fly, the protein's ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC). In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells. Alternative splicing results in multiple transcript variants encoding different isoforms.,LLGL2,HGL,Hugl-2,LGL2,Cell Biology & Developmental Biology,Cell Cycle,LLGL2
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Molecular Weight
- 114 kDa
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Gene ID
- 217325
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Pathways
- WNT Signaling
Target
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