LMAN1 antibody (AA 270-480)

Catalog No. ABIN6143266

This Rabbit Polyclonal antibody specifically detects LMAN1 in WB, IHC and IF. It exhibits reactivity toward Human.

Quick Overview for LMAN1 antibody (AA 270-480) (ABIN6143266)

Target: LMAN1 (Lectin, Mannose-Binding, 1 (LMAN1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LMAN1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-LMAN1 Antibody

Binding Specificity: AA 270-480

Sequence: PGKEPPTPDK EISEKEKEKY QEEFEHFQQE LDKKKEEFQK GHPDLQGQPA EEIFESVGDR ELRQVFEGQN RIHLEIKQLN RQLDMILDEQ RRYVSSLTEE ISKRGAGMPG QHGQITQQEL DTVVKTQHEI LRQVNEMKNS MSETVRLVSG MQHPGSAGGV YETTQHFIDI KEHLHIVKRD IDNLVQRNMP SNEKPKCPEL PPFPSCLSTV H

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 270-480 of human LMAN1 (NP_005561.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for LMAN1

Target: LMAN1 (Lectin, Mannose-Binding, 1 (LMAN1))

Alternative Name: LMAN1

Background: The protein encoded by this gene is a membrane mannose-specific lectin that cycles between the endoplasmic reticulum, endoplasmic reticulum-Golgi intermediate compartment, and cis-Golgi, functioning as a cargo receptor for glycoprotein transport. The protein has an N-terminal signal sequence, a calcium-dependent and pH -sensitive carbohydrate recognition domain, a stalk region that functions in oligomerization, a transmembrane domain, and a short cytoplasmic domain required for organelle targeting. Allelic variants of this gene are associated with the autosomal recessive disorder combined factor V-factor VIII deficiency.,LMAN1,ERGIC-53,ERGIC53,F5F8D,FMFD1,MCFD1,MR60,gp58,Signal Transduction,LMAN1

Molecular Weight: 57 kDa

Gene ID: 3998

UniProt: P49257