LNX1 antibody (AA 1-270)

Catalog No. ABIN6143286

This Rabbit Polyclonal antibody specifically detects LNX1 in IF. It exhibits reactivity toward Human.

Quick Overview for LNX1 antibody (AA 1-270) (ABIN6143286)

Target: LNX1 (Ligand of Numb-Protein X 1 (LNX1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LNX1 antibody is un-conjugated

Application: Immunofluorescence (IF)

Product Details anti-LNX1 Antibody

Binding Specificity: AA 1-270

Sequence: MNQPESANDP EPLCAVCGQA HSLEENHFYS YPEEVDDDLI CHICLQALLD PLDTPCGHTY CTLCLTNFLV EKDFCPMDRK PLVLQHCKKS SILVNKLLNK LLVTCPFREH CTQVLQRCDL EHHFQTSCKG ASHYGLTKDR KRRSQDGCPD GCASLTATAP SPEVSAAATI SLMTDEPGLD NPAYVSSAED GQPAISPVDS GRSNRTRARP FERSTIRSRS FKKINRALSV LRRTKSGSAV ANHADQGREN SENTTAPEVF PRLYHLIPDG

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human LNX1 (NP_001119800.1).

Isotype: IgG

Application Details

Application Notes: IF,1:50 - 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for LNX1

Target: LNX1 (Ligand of Numb-Protein X 1 (LNX1))

Alternative Name: LNX1

Background: This gene encodes a membrane-bound protein that is involved in signal transduction and protein interactions. The encoded product is an E3 ubiquitin-protein ligase, which mediates ubiquitination and subsequent proteasomal degradation of proteins containing phosphotyrosine binding (PTB) domains. This protein may play an important role in tumorogenesis. Alternatively spliced transcript variants encoding distinct isoforms have been described. A pseudogene, which is located on chromosome 17, has been identified for this gene.,LNX1,LNX,MPDZ,PDZRN2,Cell Biology & Developmental Biology,Ubiquitin,LNX1

Molecular Weight: 69 kDa/80 kDa

Gene ID: 84708

UniProt: Q8TBB1