LOXL1 antibody (AA 95-370)

Catalog No. ABIN6143290

This Rabbit Polyclonal antibody specifically detects LOXL1 in WB and IF. It exhibits reactivity toward Human.

Quick Overview for LOXL1 antibody (AA 95-370) (ABIN6143290)

Target: LOXL1 (Lysyl Oxidase-Like 1 (LOXL1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LOXL1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-LOXL1 Antibody

Binding Specificity: AA 95-370

Sequence: RQAPSLPLPG RVGSDTVRGQ ARHPFGFGQV PDNWREVAVG DSTGMARART SVSQQRHGGS ASSVSASAFA STYRQQPSYP QQFPYPQAPF VSQYENYDPA SRTYDQGFVY YRPAGGGVGA GAAAVASAGV IYPYQPRARY EEYGGGEELP EYPPQGFYPA PERPYVPPPP PPPDGLDRRY SHSLYSEGTP GFEQAYPDPG PEAAQAHGGD PRLGWYPPYA NPPPEAYGPP RALEPPYLPV RSSDTPPPGG ERNGAQQGRL SVGSVYRPNQ NGRGLP

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 95-370 of human LOXL1 (NP_005567.2).

Isotype: IgG

Application Details

Application Notes: WB,1:1000 - 1:3000,IF,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for LOXL1

Target: LOXL1 (Lysyl Oxidase-Like 1 (LOXL1))

Alternative Name: LOXL1

Background: This gene encodes a member of the lysyl oxidase family of proteins. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyzes the first step in the formation of crosslinks in collagen and elastin. The encoded preproprotein is proteolytically processed to generate the mature enzyme. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. Mutations in this gene are associated with exfoliation syndrome.,LOXL1,LOL,LOXL,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Endocrine & Metabolism,Amino acid metabolism,LOXL1

Molecular Weight: 63 kDa

Gene ID: 4016

UniProt: Q08397