LC3B antibody

Catalog No. ABIN6143473

Cited in 1 publication. The Rabbit Polyclonal anti-LC3B antibody (ABIN6143473) specifically detects LC3B in WB, IHC and IF. The antibody is reactive with Human samples.

Quick Overview for LC3B antibody (ABIN6143473)

Target: LC3B (MAP1LC3B) (Microtubule-Associated Protein 1 Light Chain 3 beta (MAP1LC3B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LC3B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-LC3B Antibody

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: A synthetic peptide of human LC3B

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-LC3B antibody (ABIN6143473)

Jin, Liu, Ma, Xiao, Chen: "Berberine enhances the AMPK activation and autophagy and mitigates high glucose-induced apoptosis of mouse podocytes." in: European journal of pharmacology, Vol. 794, pp. 106-114, (2017) (PubMed).

Target Details for LC3B

Target: LC3B (MAP1LC3B) (Microtubule-Associated Protein 1 Light Chain 3 beta (MAP1LC3B))

Alternative Name: MAP1LC3B

Background: The product of this gene is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and important for neurogenesis. Studies on the rat homolog implicate a role for this gene in autophagy, a process that involves the bulk degradation of cytoplasmic component.,LC3B,ATG8F,MAP1LC3B-a,MAP1A/1BLC3,MAP1LC3B,LC3A/LC3B,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Autophagy,Cytoskeleton,Microtubules,Endocrine & Metabolism,Mitochondrial metabolism,Neuroscience,Cardiovascular,Heart,ATGs,MAP1LC3B

Molecular Weight: 14 kDa

Gene ID: 81631

UniProt: Q9GZQ8

Pathways: Autophagy