MAP2K5 antibody

Catalog No. ABIN6143596

This anti-MAP2K5 antibody is a Rabbit Monoclonal antibody detecting MAP2K5 in WB. Suitable for Human.

Quick Overview for MAP2K5 antibody (ABIN6143596)

Target: MAP2K5 (Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This MAP2K5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MAP2K5 Antibody

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human MEK5

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MAP2K5

Target: MAP2K5 (Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5))

Alternative Name: MAP2K5

Background: The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been described. [provided by RefSeq, May 2011],HsT17454, MAPKK5, MEK5, PRKMK5,Cancer,Cardiovascular,Cell Biology & Developmental Biology,Cytoskeleton,Cytoskeleton_Actins,ErbB-HER Signaling Pathway,G protein signaling,G protein signaling_G-Protein-Coupled Receptors Signaling to MAPK/Erk,Heart,Heart_Cardiogenesis,IL-6 Receptor Signaling Pathway,Immunology & Inflammation,Kinase,Kinase_Serine/threonine kinases,Signal Transduction,MAP2K5

Molecular Weight: 49 kDa

Gene ID: 5607

UniProt: Q13163

Pathways: MAPK Signaling, Neurotrophin Signaling Pathway