MESDC2 antibody (AA 1-234)

Catalog No. ABIN6143742

Product Details anti-MESDC2 Antibody

Target: MESDC2 (Mesoderm Development Candidate 2 (MESDC2))

Binding Specificity: AA 1-234

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MESDC2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MAASRWARKA VVLLCASDLL LLLLLLPPPG SCAAEGSPGT PDESTPPPRK KKKDIRDYND ADMARLLEQW EKDDDIEEGD LPEHKRPSAP VDFSKIDPSK PESILKMTKK GKTLMMFVTV SGSPTEKETE EITSLWQGSL FNANYDVQRF IVGSDRAIFM LRDGSYAWEI KDFLVGQDRC ADVTLEGQVY PGKGGGSKEK NKTKQDKGKK KKEGDLKSRS SKEENRAGNK REDL

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-234 of human MESDC2 (NP_055969.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MESDC2

Target: MESDC2 (Mesoderm Development Candidate 2 (MESDC2))

Alternative Name: MESDC2 (MESDC2 Products)

Synonyms: MGC115616 antibody, MESDC2 antibody, BOCA antibody, MESD antibody, 2210015O11Rik antibody, AW537813 antibody, mKIAA0081 antibody, mesd antibody, msd antibody, zgc:158636 antibody, mesoderm development LRP chaperone antibody, mesoderm development LRP chaperone L homeolog antibody, mesoderm development candidate 2 antibody, MESD antibody, mesd.L antibody, CpipJ_CPIJ010816 antibody, Tsp_04045 antibody, mesd antibody, Mesd antibody, MESDC2 antibody

Background: Chaperone specifically assisting the folding of beta-propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs. Acts as a modulator of the Wnt pathway through chaperoning the coreceptors of the canonical Wnt pathway, LRP5 and LRP6, to the plasma membrane. Essential for specification of embryonic polarity and mesoderm induction. Plays an essential role in neuromuscular junction (NMJ formation by promoting cell-surface expression of LRP4 (By similarity. May regulate phagocytosis of apoptotic retinal pigment epithelium (RPE cells (By similarity.,MESDC2,BOCA,MESD,Cell Biology & Developmental Biology,Stem Cells,Mesenchymal Stem Cells,MESDC2

Molecular Weight: 26 kDa

Gene ID: 23184

UniProt: Q14696