MGAT5 antibody (AA 627-741)

Catalog No. ABIN6143817

The Rabbit Polyclonal anti-MGAT5 antibody is suitable to detect MGAT5 in samples from Human. It has been validated for WB.

Quick Overview for MGAT5 antibody (AA 627-741) (ABIN6143817)

Target: MGAT5 (Mannosyl (Alpha-1,6-)-Glycoprotein beta-1,6-N-Acetyl-Glucosaminyltransferase (MGAT5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MGAT5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MGAT5 Antibody

Binding Specificity: AA 627-741

Sequence: HGQVMWPPLS ALQVKLAEPG QSCKQVCQES QLICEPSFFQ HLNKDKDMLK YKVTCQSSEL AKDILVPSFD PKNKHCVFQG DLLLFSCAGA HPRHQRVCPC RDFIKGQVAL CKDCL

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 627-741 of human MGAT5 (NP_002401.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MGAT5

Target: MGAT5 (Mannosyl (Alpha-1,6-)-Glycoprotein beta-1,6-N-Acetyl-Glucosaminyltransferase (MGAT5))

Alternative Name: MGAT5

Background: The protein encoded by this gene belongs to the glycosyltransferase family. It catalyzes the addition of beta-1,6-N-acetylglucosamine to the alpha-linked mannose of biantennary N-linked oligosaccharides present on the newly synthesized glycoproteins. It is one of the most important enzymes involved in the regulation of the biosynthesis of glycoprotein oligosaccharides. Alterations of the oligosaccharides on cell surface glycoproteins cause significant changes in the adhesive or migratory behavior of a cell. Increase in the activity of this enzyme has been correlated with the progression of invasive malignancies.,MGAT5,GNT-V,GNT-VA,alpha-1,Cancer,Invasion and Metastasis,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Tight Junctions,Cytoskeleton,MGAT5

Molecular Weight: 84 kDa

Gene ID: 4249

UniProt: Q09328