MGEA5 antibody (AA 380-580)

Catalog No. ABIN6143821

This Rabbit Polyclonal antibody specifically detects MGEA5 in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for MGEA5 antibody (AA 380-580) (ABIN6143821)

Target: MGEA5 (Meningioma Expressed Antigen 5 (Hyaluronidase) (MGEA5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MGEA5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-MGEA5 Antibody

Binding Specificity: AA 380-580

Sequence: YQEPIMSQGA ALSGEPTTLT KEEEKKQPDE EPMDMVVEKQ EETDHKNDNQ ILSEIVEAKM AEELKPMDTD KESIAESKSP EMSMQEDCIS DIAPMQTDEQ TNKEQFVPGP NEKPLYTAEP VTLEDLQLLA DLFYLPYEHG PKGAQMLREF QWLRANSSVV SVNCKGKDSE KIEEWRSRAA KFEEMCGLVM GMFTRLSNCA N

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 380-580 of human MGEA5 (NP_001135906.1).

Isotype: IgG

Application Details

Application Notes: WB,1:200 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MGEA5

Target: MGEA5 (Meningioma Expressed Antigen 5 (Hyaluronidase) (MGEA5))

Alternative Name: MGEA5

Background: The dynamic modification of cytoplasmic and nuclear proteins by O-linked N-acetylglucosamine (O-GlcNAc) addition and removal on serine and threonine residues is catalyzed by OGT (MIM 300255), which adds O-GlcNAc, and MGEA5, a glycosidase that removes O-GlcNAc modifications (Gao et al., 2001 [PubMed 11148210]).[supplied by OMIM, Mar 2008],MGEA5,MEA5,NCOAT,OGA,Cancer,Tumor immunology,MGEA5

Molecular Weight: 76 kDa/95 kDa/96 kDa/102 kDa

Gene ID: 10724

UniProt: O60502

Pathways: Positive Regulation of Peptide Hormone Secretion, Regulation of Carbohydrate Metabolic Process