MSH4 antibody (AA 697-936)

Catalog No. ABIN6144062

Product Details anti-MSH4 Antibody

Target: MSH4 (MutS Homolog 4 (E. Coli) (MSH4))

Binding Specificity: AA 697-936

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MSH4 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: QIMAQIGSYV PAEYSSFRIA KQIFTRISTD DDIETNSSTF MKEMKEIAYI LHNANDKSLI LIDELGRGTN TEEGIGICYA VCEYLLSLKA FTLFATHFLE LCHIDALYPN VENMHFEVQH VKNTSRNKEA ILYTYKLSKG LTEEKNYGLK AAEVSSLPPS IVLDAKEITT QITRQILQNQ RSTPEMERQR AVYHLATRLV QTARNSQLDP DSLRIYLSNL KKKYKEDFPR TEQVPEKTEE

Cross-Reactivity: Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 697-936 of human MSH4 (NP_002431.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MSH4

Target: MSH4 (MutS Homolog 4 (E. Coli) (MSH4))

Alternative Name: MSH4 (MSH4 Products)

Synonyms: MSH4 antibody, 4930485C04Rik antibody, AV144863 antibody, mMsh4 antibody, mutS homolog 4 antibody, mutS protein homolog 4 antibody, Msh4 antibody, MSH4 antibody, msh4 antibody, LOC575381 antibody, LOC100639599 antibody

Background: This gene encodes a member of the DNA mismatch repair mutS family. This member is a meiosis-specific protein that is not involved in DNA mismatch correction, but is required for reciprocal recombination and proper segregation of homologous chromosomes at meiosis I. This protein and MSH5 form a heterodimer which binds uniquely to a Holliday Junction and its developmental progenitor, thus provoking ADP-ATP exchange, and stabilizing the interaction between parental chromosomes during meiosis double-stranded break repair.,MSH4,Epigenetics & Nuclear Signaling,DNA Damage & Repair,MSH4

Molecular Weight: 104 kDa

Gene ID: 4438

UniProt: O15457