MYO5A antibody (AA 950-1150)

Catalog No. ABIN6144285

The Rabbit Polyclonal anti-MYO5A antibody has been validated for WB and IF. It is suitable to detect MYO5A in samples from Human.

Quick Overview for MYO5A antibody (AA 950-1150) (ABIN6144285)

Target: MYO5A (Myosin VA (MYO5A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYO5A antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-MYO5A Antibody

Binding Specificity: AA 950-1150

Sequence: LTNLEGIYNS ETEKLRSDLE RLQLSEEEAK VATGRVLSLQ EEIAKLRKDL EQTRSEKKCI EEHADRYKQE TEQLVSNLKE ENTLLKQEKE ALNHRIVQQA KEMTETMEKK LVEETKQLEL DLNDERLRYQ NLLNEFSRLE ERYDDLKEEM TLMVHVPKPG HKRTDSTHSS NESEYIFSSE IAEMEDIPSR TEEPSEKKVP L

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 950-1150 of human MYO5A (NP_000250.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:100

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MYO5A

Target: MYO5A (Myosin VA (MYO5A))

Alternative Name: MYO5A

Background: This gene is one of three myosin V heavy-chain genes, belonging to the myosin gene superfamily. Myosin V is a class of actin-based motor proteins involved in cytoplasmic vesicle transport and anchorage, spindle-pole alignment and mRNA translocation. The protein encoded by this gene is abundant in melanocytes and nerve cells. Mutations in this gene cause Griscelli syndrome type-1 (GS1), Griscelli syndrome type-3 (GS3) and neuroectodermal melanolysosomal disease, or Elejalde disease. Multiple alternatively spliced transcript variants encoding different isoforms have been reported, but the full-length nature of some variants has not been determined.,MYO5A,GS1,MYH12,MYO5,MYR12,myosin VA,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Motor Proteins,Endocrine & Metabolism,Mitochondrial metabolism,Neuroscience,MYO5A

Molecular Weight: 212 kDa/215 kDa/218 kDa

Gene ID: 4644

UniProt: Q9Y4I1

Pathways: Hormone Transport, Peptide Hormone Metabolism