MYO5A antibody (AA 1760-1840)

Catalog No. ABIN7222624

The Rabbit Polyclonal anti-MYO5A antibody is suitable to detect MYO5A in samples from Human, Mouse and Rat. It has been validated for WB and IHC.

Quick Overview for MYO5A antibody (AA 1760-1840) (ABIN7222624)

Target: MYO5A (Myosin VA (MYO5A))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYO5A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-MYO5A Antibody

Binding Specificity: AA 1760-1840

Purpose: Rabbit Anti-Myosin VA Polyclonal Antibody

Specificity: Myosin VA Polyclonal Antibody detects endogenous levels of Myosin VA protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human Myosin VA at AA range: 1760-1840

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:50-300

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for MYO5A

Target: MYO5A (Myosin VA (MYO5A))

Alternative Name: Myosin VA

Background: MYO5A, MYH12, Unconventional myosin-Va, Dilute myosin heavy chain, non-muscle, Myosin heavy chain 12, Myosin-12, MyoxinMYO5A is one of three myosin V heavy-chain genes, belonging to the myosin gene superfamily. Myosin V is a class of actin-based motor proteins involved in cytoplasmic vesicle transport and anchorage, spindle-pole alignment and mRNA translocation. The protein encoded by MYO5A is abundant in melanocytes and nerve cells. Mutations in this gene cause Griscelli syndrome type-1 (GS1), Griscelli syndrome type-3 (GS3) and neuroectodermal melanolysosomal disease, or Elejalde disease. Multiple alternatively spliced transcript variants encoding different isoforms have been reported, but the full-length nature of some variants has not been determined.

Molecular Weight: 220kD

Gene ID: 4644

UniProt: Q9Y4I1

Pathways: Hormone Transport, Peptide Hormone Metabolism