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NAA50 antibody (AA 1-169)

NAA50 Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6144327
  • Target See all NAA50 Antibodies
    NAA50 (N(alpha)-Acetyltransferase 50, NatE Catalytic Subunit (NAA50))
    Binding Specificity
    • 9
    • 8
    • 6
    • 2
    • 2
    AA 1-169
    Reactivity
    • 23
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 23
    Rabbit
    Clonality
    • 23
    Polyclonal
    Conjugate
    • 13
    • 2
    • 2
    • 2
    • 2
    • 2
    This NAA50 antibody is un-conjugated
    Application
    • 21
    • 14
    • 13
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Sequence
    MKGSRIELGD VTPHNIKQLK RLNQVIFPVS YNDKFYKDVL EVGELAKLAY FNDIAVGAVC CRVDHSQNQK RLYIMTLGCL APYRRLGIGT KMLNHVLNIC EKDGTFDNIY LHVQISNESA IDFYRKFGFE IIETKKNYYK RIEPADAHVL QKNLKVPSGQ NADVQKTDN
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Polyclonal Antibodies
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-169 of human NAA50 (NP_079422.1).
    Isotype
    IgG
    Top Product
    Discover our top product NAA50 Primary Antibody
  • Application Notes
    WB,1:500 - 1:2000,IF,1:50 - 1:200
    Comment

    HIGH QUALITY

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    NAA50 (N(alpha)-Acetyltransferase 50, NatE Catalytic Subunit (NAA50))
    Alternative Name
    NAA50 (NAA50 Products)
    Synonyms
    MAK3 antibody, NAT13 antibody, NAT5 antibody, SAN antibody, hNAT5 antibody, hSAN antibody, 2600005K24Rik antibody, 2810441M03Rik antibody, AW112078 antibody, Mak3 antibody, Mak3p antibody, Nat13 antibody, Nat5 antibody, San antibody, DKFZp469M1032 antibody, san antibody, mak3 antibody, nat5 antibody, nat13 antibody, MGC80671 antibody, N(alpha)-acetyltransferase 50, NatE catalytic subunit antibody, N(alpha)-acetyltransferase 50, NatE catalytic subunit L homeolog antibody, NAA50 antibody, Naa50 antibody, naa50.L antibody
    Background
    N-alpha-acetyltransferase that acetylates the N-terminus of proteins that retain their initiating methionine. Has a broad substrate specificity: able to acetylate the initiator methionine of most peptides, except for those with a proline in second position. Also displays N-epsilon-acetyltransferase activity by mediating acetylation of the side chain of specific lysines on proteins. Autoacetylates in vivo. The relevance of N-epsilon-acetyltransferase activity is however unclear: able to acetylate H4 in vitro, but this result has not been confirmed in vivo. Component of N-alpha-acetyltransferase complexes containing NAA10 and NAA15, which has N-alpha-acetyltransferase activity. Does not influence the acetyltransferase activity of NAA10. However, it negatively regulates the N-alpha-acetyltransferase activity of the N-terminal acetyltransferase A complex (also called the NatA complex. The multiprotein complexes probably constitute the major contributor for N-terminal acetylation at the ribosome exit tunnel, with NAA10 acetylating all amino termini that are devoid of methionine and NAA50 acetylating other peptides. Required for sister chromatid cohesion during mitosis by promoting binding of CDCA5/sororin to cohesin: may act by counteracting the function of NAA10.,NAA50,MAK3,NAT13,NAT13P,NAT5,NAT5P,SAN,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,NAA50
    Molecular Weight
    9 kDa/19 kDa
    Gene ID
    80218
    UniProt
    Q9GZZ1
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