NEK3 antibody (AA 267-506)

Catalog No. ABIN6144520

The Rabbit Polyclonal anti-NEK3 antibody (ABIN6144520) specifically detects NEK3 in WB. The antibody is reactive with Human samples.

Quick Overview for NEK3 antibody (AA 267-506) (ABIN6144520)

Target: NEK3 (NIMA related kinase 3 (NEK3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NEK3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NEK3 Antibody

Binding Specificity: AA 267-506

Sequence: PEIIMEYGEE VLEEIKNSKH NTPRKKTNPS RIRIALGNEA STVQEEEQDR KGSHTDLESI NENLVESALR RVNREEKGNK SVHLRKASSP NLHRRQWEKN VPNTALTALE NASILTSSLT AEDDRGGSVI KYSKNTTRKQ WLKETPDTLL NILKNADLSL AFQTYTIYRP GSEGFLKGPL SEETEASDSV DGGHDSVILD PERLEPGLDE EDTDFEEEDD NPDWVSELKK RAGWQGLCDR

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 267-506 of human NEK3 (NP_689933.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for NEK3

Target: NEK3 (NIMA related kinase 3 (NEK3))

Alternative Name: NEK3

Background: This gene encodes a member of the NimA (never in mitosis A) family of serine/threonine protein kinases. The encoded protein differs from other NimA family members in that it is not cell cycle regulated and is found primarily in the cytoplasm. The kinase is activated by prolactin stimulation, leading to phosphorylation of VAV2 guanine nucleotide exchange factor, paxillin, and activation of the RAC1 GTPase. Multiple transcript variants encoding different isoforms have been found for this gene.,NEK3,HSPK36,Cancer,Signal Transduction,Kinase,Serine/threonine kinases,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,NEK3

Molecular Weight: 55 kDa/57 kDa

Gene ID: 4752

UniProt: P51956