NFS1 antibody (AA 208-457)

Catalog No. ABIN6144595

The Rabbit Polyclonal anti-NFS1 antibody has been validated for WB, IHC and IF. It is suitable to detect NFS1 in samples from Human.

Quick Overview for NFS1 antibody (AA 208-457) (ABIN6144595)

Target: NFS1 (NFS1, Cysteine Desulfurase (NFS1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NFS1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-NFS1 Antibody

Binding Specificity: AA 208-457

Sequence: EIGVKQPIAE IGRICSSRKV YFHTDAAQAV GKIPLDVNDM KIDLMSISGH KIYGPKGVGA IYIRRRPRVR VEALQSGGGQ ERGMRSGTVP TPLVVGLGAA CEVAQQEMEY DHKRISKLSE RLIQNIMKSL PDVVMNGDPK HHYPGCINLS FAYVEGESLL MALKDVALSS GSACTSASLE PSYVLRAIGT DEDLAHSSIR FGIGRFTTEE EVDYTVEKCI QHVKRLREMS PLWEMVQDGI DLKSIKWTQH

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 208-457 of human NFS1 (NP_066923.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for NFS1

Target: NFS1 (NFS1, Cysteine Desulfurase (NFS1))

Alternative Name: NFS1

Background: Iron-sulfur clusters are required for the function of many cellular enzymes. The proteins encoded by this gene supply inorganic sulfur to these clusters by removing the sulfur from cysteine, creating alanine in the process. This gene uses alternate in-frame translation initiation sites to generate mitochondrial forms and cytoplasmic/nuclear forms. Selection of the alternative initiation sites is determined by the cytosolic pH . The encoded proteins belong to the class-V family of pyridoxal phosphate-dependent aminotransferases. Alternatively spliced transcript variants have been described.,NFS1,HUSSY-08,IscS,NIFS,Signal Transduction,Endocrine & Metabolism,Amino acid metabolism,Neuroscience,Neurodegenerative Diseases Markers,Other Neurological disorders,NFS1

Molecular Weight: 44 kDa/50 kDa

Gene ID: 9054

UniProt: Q9Y697

Pathways: Transition Metal Ion Homeostasis