NPC2 antibody (AA 20-151)

Catalog No. ABIN6144762

This Rabbit Polyclonal antibody specifically detects NPC2 in WB. It exhibits reactivity toward Human.

Quick Overview for NPC2 antibody (AA 20-151) (ABIN6144762)

Target: NPC2 (Niemann-Pick Disease, Type C2 (NPC2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NPC2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NPC2 Antibody

Binding Specificity: AA 20-151

Sequence: EPVQFKDCGS VDGVIKEVNV SPCPTQPCQL SKGQSYSVNV TFTSNIQSKS SKAVVHGILM GVPVPFPIPE PDGCKSGINC PIQKDKTYSY LNKLPVKSEY PSIKLVVEWQ LQDDKNQSLF CWEIPVQIVS HL

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 20-151 of human NPC2 (NP_006423.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for NPC2

Target: NPC2 (Niemann-Pick Disease, Type C2 (NPC2))

Alternative Name: NPC2

Background: This gene encodes a protein containing a lipid recognition domain. The encoded protein may function in regulating the transport of cholesterol through the late endosomal/lysosomal system. Mutations in this gene have been associated with Niemann-Pick disease, type C2 and frontal lobe atrophy.,NPC2,EDDM1,HE1,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,Cholesterol Metabolism,Neuroscience,Neurodegenerative Diseases,Cardiovascular,Lipids,NPC2

Molecular Weight: 13 kDa/16 kDa

Gene ID: 10577

UniProt: P61916

Pathways: SARS-CoV-2 Protein Interactome