Lactate Dehydrogenase A antibody

Catalog No. ABIN614512

This Mouse Monoclonal antibody specifically detects Lactate Dehydrogenase A in IHC (p). It exhibits reactivity toward Human.

Quick Overview for Lactate Dehydrogenase A antibody (ABIN614512)

Target: Lactate Dehydrogenase A (LDHA)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Lactate Dehydrogenase A antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: N-a

Product Details anti-Lactate Dehydrogenase A Antibody

Specificity: Recognizes Lactate Dehydrogenase A (LDHA)

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Protein G Chromatography

Immunogen: Human LDHA

Isotype: IgG2b

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.42 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Lactate Dehydrogenase A

Target: Lactate Dehydrogenase A (LDHA)

Alternative Name: LDHA

Background: Lactate dehydrogenase A catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. LDHA is found predominantly in muscle tissue and belongs to the lactate dehydrogenase family. Mutations in LDHA have been linked to exertional myoglobinuria.Synonyms: Cell proliferation-inducing gene 19 protein, L-lactate dehydrogenase A chain, LDH muscle subunit, LDH-A, LDH-M, NY-REN-59, PIG19, Renal carcinoma antigen NY-REN-59

Gene ID: 3939

NCBI Accession: NP_005557

UniProt: P00338

Pathways: Warburg Effect