PAX6 antibody (AA 1-300)

Catalog No. ABIN6145260

This anti-PAX6 antibody is a Rabbit Polyclonal antibody detecting PAX6 in WB and IF. Suitable for Human. This Primary Antibody has been cited in 3+ publications.

Quick Overview for PAX6 antibody (AA 1-300) (ABIN6145260)

Target: PAX6 (Paired Box 6 (PAX6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAX6 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-PAX6 Antibody

Binding Specificity: AA 1-300

Sequence: MQNSHSGVNQ LGGVFVNGRP LPDSTRQKIV ELAHSGARPC DISRILQVSN GCVSKILGRY YETGSIRPRA IGGSKPRVAT PEVVSKIAQY KRECPSIFAW EIRDRLLSEG VCTNDNIPSV SSINRVLRNL ASEKQQMGAD GMYDKLRMLN GQTGSWGTRP GWYPGTSVPG QPTQDGCQQQ EGGGENTNSI SSNGEDSDEA QMRLQLKRKL QRNRTSFTQE QIEALEKEFE RTHYPDVFAR ERLAAKIDLP EARIQVWFSN RRAKWRREEK LRNQRRQASN TPSHIPISSS FSTSVYQPIP

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human PAX6 (NP_000271.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-PAX6 antibody (ABIN6145260)

Zhang, Xu, Xu, Wei, Xu: "Protein kinase A inhibitor, H89, significantly enhances survival rate of dissociated human embryonic stem cells following cryopreservation." in: Cell proliferation, Vol. 49, Issue 5, pp. 589-98, (2017) (PubMed).

Zhang, Xu, Xu, Wei, Xu: "Protein kinase A inhibitor, H89, enhances survival and clonogenicity of dissociated human embryonic stem cells through Rho-associated coiled-coil containing protein kinase (ROCK) inhibition." in: Human reproduction (Oxford, England), Vol. 31, Issue 4, pp. 832-43, (2016) (PubMed).

Xu, Zhang, Xu, Wei, Xu: "Sensitivity of human embryonic stem cells to different conditions during cryopreservation." in: Cryobiology, Vol. 71, Issue 3, pp. 486-92, (2016) (PubMed).

Target Details for PAX6

Target: PAX6 (Paired Box 6 (PAX6))

Alternative Name: PAX6

Background: This gene encodes a homeobox and paired domain-containing protein that binds DNA and functions as a regulator of transcription. Activity of this protein is key in the development of neural tissues, particularly the eye. This gene is regulated by multiple enhancers located up to hundreds of kilobases distant from this locus. Mutations in this gene or in the enhancer regions can cause ocular disorders such as aniridia and Peter's anomaly. Use of alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms.,AN,AN2,ASGD5,D11S812E,FVH1,MGDA,WAGR,PAX6,Epigenetics & Nuclear Signaling,Transcription Factors,Signal Transduction,MAPK-Erk Signaling Pathway,MAPK-P38 Signaling Pathway,Cell Biology & Developmental Biology,Neuroscience,Cell Type Marker,Stem Cells,Neural Stem Cell marker,PAX6

Molecular Weight: 46 kDa/48 kDa

Gene ID: 5080

UniProt: P26367

Pathways: Peptide Hormone Metabolism, Carbohydrate Homeostasis