PCDH15 antibody (AA 160-400)

Catalog No. ABIN6145289

This anti-PCDH15 antibody is a Rabbit Polyclonal antibody detecting PCDH15 in WB and IHC. Suitable for Human.

Quick Overview for PCDH15 antibody (AA 160-400) (ABIN6145289)

Target: PCDH15 (Protocadherin-15 (PCDH15))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCDH15 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-PCDH15 Antibody

Binding Specificity: AA 160-400

Sequence: TVNELTPVGT TIFTGFSGDN GATDIDDGPN GQIEYVIQYN PDDPTSNDTF EIPLMLTGNI VLRKRLNYED KTRYFVIIQA NDRAQNLNER RTTTTTLTVD VLDGDDLGPM FLPCVLVPNT RDCRPLTYQA AIPELRTPEE LNPIIVTPPI QAIDQDRNIQ PPSDRPGILY SILVGTPEDY PRFFHMHPRT AELSLLEPVN RDFHQKFDLV IKAEQDNGHP LPAFAGLHIE ILDENNQSPY F

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 160-400 of human PCDH15 (NP_001136235.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:100 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PCDH15

Target: PCDH15 (Protocadherin-15 (PCDH15))

Alternative Name: PCDH15

Background: This gene is a member of the cadherin superfamily. Family members encode integral membrane proteins that mediate calcium-dependent cell-cell adhesion. It plays an essential role in maintenance of normal retinal and cochlear function. Mutations in this gene result in hearing loss and Usher Syndrome Type IF (USH1F). Extensive alternative splicing resulting in multiple isoforms has been observed in the mouse ortholog. Similar alternatively spliced transcripts are inferred to occur in human, and additional variants are likely to occur.,PCDH15,CDHR15,DFNB23,USH1F,PCDH15

Molecular Weight: 92 kDa/106 kDa/185 kDa/197 kDa/216 kDa

Gene ID: 65217

UniProt: Q96QU1

Pathways: Sensory Perception of Sound