PDE8A antibody (AA 1-120)

Catalog No. ABIN6145368

The Rabbit Polyclonal anti-PDE8A antibody has been validated for WB. It is suitable to detect PDE8A in samples from Human.

Quick Overview for PDE8A antibody (AA 1-120) (ABIN6145368)

Target: PDE8A (phosphodiesterase 8A (PDE8A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDE8A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PDE8A Antibody

Binding Specificity: AA 1-120

Sequence: MGCAPSIHIS ERLVAEDAPS PAAPPLSSGG PRLPQGQKTA ALPRTRGAGL LESELRDGSG KKVAVADVQF GPMRFHQDQL QVLLVFTKED NQCNGFCRAC EKAGFKCTVT KEAQAVLACF

Cross-Reactivity: Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human PDE8A (NP_002596.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PDE8A

Target: PDE8A (phosphodiesterase 8A (PDE8A))

Alternative Name: PDE8A

Background: The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE8 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,PDE8A,HsT19550,Signal Transduction,PDE8A

Molecular Weight: 25 kDa/29 kDa/86 kDa/88 kDa/93 kDa

Gene ID: 5151

UniProt: O60658

Pathways: cAMP Metabolic Process