PDIA2 antibody (AA 326-525)

Catalog No. ABIN6145387

The Rabbit Polyclonal anti-PDIA2 antibody has been validated for WB and IF. It is suitable to detect PDIA2 in samples from Human.

Quick Overview for PDIA2 antibody (AA 326-525) (ABIN6145387)

Target: PDIA2 (Protein Disulfide Isomerase Family A, Member 2 (PDIA2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDIA2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-PDIA2 Antibody

Binding Specificity: AA 326-525

Sequence: FGLKAEAAPT LRLVNLETTK KYAPVDGGPV TAASITAFCH AVLNGQVKPY LLSQEIPPDW DQRPVKTLVG KNFEQVAFDE TKNVFVKFYA PWCTHCKEMA PAWEALAEKY QDHEDIIIAE LDATANELDA FAVHGFPTLK YFPAGPGRKV IEYKSTRDLE TFSKFLDNGG VLPTEEPPEE PAAPFPEPPA NSTMGSKEEL

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 326-525 of human PDIA2 (NP_006840.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PDIA2

Target: PDIA2 (Protein Disulfide Isomerase Family A, Member 2 (PDIA2))

Alternative Name: PDIA2

Background: This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, two catalytically active thioredoxin (TRX) domains, two TRX-like domains and a C-terminal ER-retention sequence. The protein plays a role in the folding of nascent proteins in the endoplasmic reticulum by forming disulfide bonds through its thiol isomerase, oxidase, and reductase activity.,PDIA2,PDA2,PDI,PDIP,PDIR,Cancer,Endocrine & Metabolism,PDIA2

Molecular Weight: 57 kDa/58 kDa

Gene ID: 64714

UniProt: Q13087

Pathways: Maintenance of Protein Location, Cell RedoxHomeostasis, Unfolded Protein Response