PINK1 antibody (AA 282-581)
Quick Overview for PINK1 antibody (AA 282-581) (ABIN6145666)
Target
See all PINK1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 282-581
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Sequence
- TSSVPLLPGA LVDYPDVLPS RLHPEGLGHG RTLFLVMKNY PCTLRQYLCV NTPSPRLAAM MLLQLLEGVD HLVQQGIAHR DLKSDNILVE LDPDGCPWLV IADFGCCLAD ESIGLQLPFS SWYVDRGGNG CLMAPEVSTA RPGPRAVIDY SKADAWAVGA IAYEIFGLVN PFYGQGKAHL ESRSYQEAQL PALPESVPPD VRQLVRALLQ REASKRPSAR VAANVLHLSL WGEHILALKN LKLDKMVGWL LQQSAATLLA NRLTEKCCVE TKMKMLFLAN LECETLCQAA LLLCSWRAAL
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Cross-Reactivity
- Human, Mouse, Rat
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Characteristics
- Polyclonal Antibodies
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 282-581 of human PINK1 (NP_115785.1).
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Isotype
- IgG
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Application Notes
- WB,1:500 - 1:2000,IF,1:50 - 1:200
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Comment
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HIGH QUALITY
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- PINK1 (PTEN Induced Putative Kinase 1 (PINK1))
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Alternative Name
- PINK1
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Background
- This gene encodes a serine/threonine protein kinase that localizes to mitochondria. It is thought to protect cells from stress-induced mitochondrial dysfunction. Mutations in this gene cause one form of autosomal recessive early-onset Parkinson disease.,PINK1,BRPK,PARK6,Signal Transduction,Kinase,Cell Biology & Developmental Biology,Autophagy,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Mitophagy fission and fusion,Neuroscience,Neurodegenerative Diseases,Dopamine Signaling in Parkinson's Disease,Neurodegenerative Diseases Markers,Cardiovascular,Heart,Cardiac metabolism,Mitochondrial Control of Autophagy,PINK1
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Molecular Weight
- 30 kDa/62 kDa
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Gene ID
- 65018
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UniProt
- Q9BXM7
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Pathways
- Autophagy
Target
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