PLA2G1B antibody (AA 23-148)

Catalog No. ABIN6145724

The Rabbit Polyclonal anti-PLA2G1B antibody (ABIN6145724) specifically detects PLA2G1B in WB and IHC. The antibody is reactive with Human samples.

Quick Overview for PLA2G1B antibody (AA 23-148) (ABIN6145724)

Target: PLA2G1B (Phospholipase A2, Group IB (PLA2G1B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLA2G1B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-PLA2G1B Antibody

Binding Specificity: AA 23-148

Sequence: AVWQFRKMIK CVIPGSDPFL EYNNYGCYCG LGGSGTPVDE LDKCCQTHDN CYDQAKKLDS CKFLLDNPYT HTYSYSCSGS AITCSSKNKE CEAFICNCDR NAAICFSKAP YNKAHKNLDT KKYCQS

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 23-148 of human PLA2G1B (NP_000919.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:100 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PLA2G1B

Target: PLA2G1B (Phospholipase A2, Group IB (PLA2G1B))

Alternative Name: PLA2G1B

Background: This gene encodes a secreted member of the phospholipase A2 (PLA2) class of enzymes, which is produced by the pancreatic acinar cells. The encoded calcium-dependent enzyme catalyzes the hydrolysis of the sn-2 position of membrane glycerophospholipids to release arachidonic acid (AA) and lysophospholipids. AA is subsequently converted by downstream metabolic enzymes to several bioactive lipophilic compounds (eicosanoids), including prostaglandins (PGs) and leukotrienes (LTs). The enzyme may be involved in several physiological processes including cell contraction, cell proliferation and pathological response.,PLA2G1B,PLA2,PLA2A,PPLA2,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,Endocrine & Metabolism,Lipid Metabolism,PLA2G1B

Molecular Weight: 16 kDa

Gene ID: 5319

UniProt: P04054

Pathways: Inositol Metabolic Process, VEGF Signaling