PLA2G6 antibody (AA 550-650)

Catalog No. ABIN6145732

Product Details anti-PLA2G6 Antibody

Target: PLA2G6 (Phospholipase A2, Group VI (Cytosolic, Calcium-Independent) (PLA2G6))

Binding Specificity: AA 550-650

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLA2G6 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: RGSRPYESGP LEEFLKREFG EHTKMTDVRK PKVMLTGTLS DRQPAELHLF RNYDAPETVR EPRFNQNVNL RPPAQPSDQL VWRAARSSGA APTYFRPNGR F

Cross-Reactivity: Rat

Characteristics: Polyclonal Antibodies

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 550-650 of human PLA2G6 (NP_003551.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PLA2G6

Target: PLA2G6 (Phospholipase A2, Group VI (Cytosolic, Calcium-Independent) (PLA2G6))

Alternative Name: PLA2G6 (PLA2G6 Products)

Background: The protein encoded by this gene is an A2 phospholipase, a class of enzyme that catalyzes the release of fatty acids from phospholipids. The encoded protein may play a role in phospholipid remodelling, arachidonic acid release, leukotriene and prostaglandin synthesis, fas-mediated apoptosis, and transmembrane ion flux in glucose-stimulated B-cells. Several transcript variants encoding multiple isoforms have been described, but the full-length nature of only three of them have been determined to date.,PLA2G6,CaI-PLA2,GVI,INAD1,IPLA2-VIA,NBIA2,NBIA2A,NBIA2B,PARK14,PLA2,PNPLA9,iPLA2,iPLA2beta,Signal Transduction,PLA2G6

Molecular Weight: 46 kDa/53 kDa/84 kDa/89 kDa

Gene ID: 8398

UniProt: O60733

Pathways: Positive Regulation of Peptide Hormone Secretion