PLOD3 antibody (AA 25-280)

Catalog No. ABIN6145791

This anti-PLOD3 antibody is a Rabbit Polyclonal antibody detecting PLOD3 in WB, IHC and IF. Suitable for Human.

Quick Overview for PLOD3 antibody (AA 25-280) (ABIN6145791)

Target: PLOD3 (Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase 3 (PLOD3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLOD3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-PLOD3 Antibody

Binding Specificity: AA 25-280

Sequence: SDRPRGRDPV NPEKLLVITV ATAETEGYLR FLRSAEFFNY TVRTLGLGEE WRGGDVARTV GGGQKVRWLK KEMEKYADRE DMIIMFVDSY DVILAGSPTE LLKKFVQSGS RLLFSAESFC WPEWGLAEQY PEVGTGKRFL NSGGFIGFAT TIHQIVRQWK YKDDDDDQLF YTRLYLDPGL REKLSLNLDH KSRIFQNLNG ALDEVVLKFD RNRVRIRNVA YDTLPIVVHG NGPTKLQLNY LGNYVPNGWT PEGGCG

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 25-280 of human PLOD3 (NP_001075.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PLOD3

Target: PLOD3 (Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase 3 (PLOD3))

Alternative Name: PLOD3

Background: The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity.,PLOD3,LH3,Epigenetics & Nuclear Signaling,PLOD3

Molecular Weight: 84 kDa

Gene ID: 8985

UniProt: O60568