PPAN antibody (AA 1-300)

Catalog No. ABIN6145994

The Rabbit Polyclonal anti-PPAN antibody is suitable to detect PPAN in samples from Human. It has been validated for WB, IHC and IF.

Quick Overview for PPAN antibody (AA 1-300) (ABIN6145994)

Target: PPAN (Peter Pan Homolog (PPAN))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPAN antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-PPAN Antibody

Binding Specificity: AA 1-300

Sequence: MGQSGRSRHQ KRARAQAQLR NLEAYAANPH SFVFTRGCTG RNIRQLSLDV RRVMEPLTAS RLQVRKKNSL KDCVAVAGPL GVTHFLILSK TETNVYFKLM RLPGGPTLTF QVKKYSLVRD VVSSLRRHRM HEQQFAHPPL LVLNSFGPHG MHVKLMATMF QNLFPSINVH KVNLNTIKRC LLIDYNPDSQ ELDFRHYSIK VVPVGASRGM KKLLQEKFPN MSRLQDISEL LATGAGLSES EAEPDGDHNI TELPQAVAGR GNMRAQQSAV RLTEIGPRMT LQLIKVQEGV GEGKVMFHSF

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human PPAN (NP_064615.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PPAN

Target: PPAN (Peter Pan Homolog (PPAN))

Alternative Name: PPAN

Background: The protein encoded by this gene is an evolutionarily conserved protein similar to yeast SSF1 as well as to the gene product of the Drosophila gene peter pan (ppan). SSF1 is known to be involved in the second step of mRNA splicing. Both SSF1 and ppan are essential for cell growth and proliferation. Exogenous expression of this gene was reported to reduce the anchorage-independent growth of some tumor cells. Read-through transcription of this gene with P2RY11/P2Y(11), an adjacent downstream gene that encodes an ATP receptor, has been found. These read-through transcripts are ubiquitously present and up-regulated during granulocyte differentiation.,PPAN,BXDC3,SSF,SSF-1,SSF1,SSF2,Epigenetics & Nuclear Signaling,RNA Binding,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),PPAN

Molecular Weight: 51 kDa/53 kDa/58 kDa

Gene ID: 56342

UniProt: Q9NQ55