PRMT6 antibody (AA 1-375)

Catalog No. ABIN6146232

Product Details anti-PRMT6 Antibody

Target: PRMT6 (Protein Arginine Methyltransferase 6 (PRMT6))

Binding Specificity: AA 1-375

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRMT6 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Sequence: MSQPKKRKLE SGGGGEGGEG TEEEDGAERE AALERPRRTK RERDQLYYEC YSDVSVHEEM IADRVRTDAY RLGILRNWAA LRGKTVLDVG AGTGILSIFC AQAGARRVYA VEASAIWQQA REVVRFNGLE DRVHVLPGPV ETVELPEQVD AIVSEWMGYG LLHESMLSSV LHARTKWLKE GGLLLPASAE LFIAPISDQM LEWRLGFWSQ VKQHYGVDMS CLEGFATRCL MGHSEIVVQG LSGEDVLARP QRFAQLELSR AGLEQELEAG VGGRFRCSCY GSAPMHGFAI WFQVTFPGGE SEKPLVLSTS PFHPATHWKQ ALLYLNEPVQ VEQDTDVSGE ITLLPSRDNP RRLRVLLRYK VGDQEEKTKD FAMED

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-375 of human PRMT6 (NP_060607.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PRMT6

Target: PRMT6 (Protein Arginine Methyltransferase 6 (PRMT6))

Alternative Name: PRMT6 (PRMT6 Products)

Synonyms: CG9927 antibody, DART6 antibody, Dmel\\CG9927 antibody, PRMT6 antibody, HRMT1L6 antibody, ARABIDOPSIS THALIANA PROTEIN ARGININE METHYLTRANSFERASE 6 antibody, ATPRMT6 antibody, protein arginine methyltransferase 6 antibody, DKFZp459B1431 antibody, Hrmt1l6 antibody, hrmt1l6 antibody, hrmt6 antibody, im:6908706 antibody, AW124876 antibody, BB233495 antibody, Arginine methyltransferase 6 antibody, protein arginine methyltransferase 6 antibody, protein arginine methyltransferase 6 S homeolog antibody, arginine N-methyltransferase, type I antibody, protein arginine N-methyltransferase 6 antibody, Art6 antibody, PRMT6 antibody, prmt6.S antibody, prmt6 antibody, Prmt6 antibody

Background: The protein encoded by this gene belongs to the arginine N-methyltransferase family, which catalyze the sequential transfer of methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins, to form methylated arginine derivatives and S-adenosyl-L-homocysteine. This protein can catalyze both, the formation of omega-N monomethylarginine and asymmetrical dimethylarginine, with a strong preference for the latter. It specifically mediates the asymmetric dimethylation of Arg2 of histone H3, and the methylated form represents a specific tag for epigenetic transcriptional repression. This protein also forms a complex with, and methylates DNA polymerase beta, resulting in stimulation of polymerase activity by enhancing DNA binding and processivity.,PRMT6,HRMT1L6,Epigenetics & Nuclear Signaling,Chromatin Modifying Enzymes,Methylation,PRMT6

Molecular Weight: 32 kDa/41 kDa

Gene ID: 55170

UniProt: Q96LA8