PSMD13 antibody (AA 1-250)

Catalog No. ABIN6146337

Product Details anti-PSMD13 Antibody

Target: PSMD13 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 13 (PSMD13))

Binding Specificity: AA 1-250

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSMD13 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequence: MKDVPGFLQQ SQNSGPGQPA VWHRLEELYT KKLWHQLTLQ VLDFVQDPCF AQGDGLIKLY ENFISEFEHR VNPLSLVEII LHVVRQMTDP NVALTFLEKT REKVKSSDEA VILCKTAIGA LKLNIGDLQV TKETIEDVEE MLNNLPGVTS VHSRFYDLSS KYYQTIGNHA SYYKDALRFL GCVDIKDLPV SEQQERAFTL GLAGLLGEGV FNFGELLMHP VLESLRNTDR QWLIDTLYAF NSGNVERFQT

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human PSMD13 (NP_002808.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PSMD13

Target: PSMD13 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 13 (PSMD13))

Alternative Name: PSMD13 (PSMD13 Products)

Synonyms: HSPC027 antibody, Rpn9 antibody, S11 antibody, p40.5 antibody, zgc:56377 antibody, zgc:77482 antibody, MGC84231 antibody, MGC69415 antibody, DDBDRAFT_0186342 antibody, DDBDRAFT_0233004 antibody, DDB_0186342 antibody, DDB_0233004 antibody, proteasome 26S subunit, non-ATPase 13 antibody, proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 antibody, proteasome 26S subunit, non-ATPase 13 S homeolog antibody, 26S proteasome non-ATPase regulatory subunit 13 antibody, PSMD13 antibody, Psmd13 antibody, psmd13 antibody, psmd13.S antibody, psmD13 antibody

Background: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. Two transcripts encoding different isoforms have been described.,PSMD13,HSPC027,Rpn9,S11,p40.5,Cell Biology & Developmental Biology,Ubiquitin,PSMD13

Molecular Weight: 42 kDa

Gene ID: 5719

UniProt: Q9UNM6

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway