PYGB antibody (AA 544-843)

Catalog No. ABIN6146522

This anti-PYGB antibody is a Rabbit Polyclonal antibody detecting PYGB in WB, IF and IP. Suitable for Human.

Quick Overview for PYGB antibody (AA 544-843) (ABIN6146522)

Target: PYGB (GPBB) (phosphorylase, Glycogen, Brain (GPBB))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PYGB antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)

Product Details anti-PYGB Antibody

Binding Specificity: AA 544-843

Sequence: LKFSAFLEKE YKVKINPSSM FDVHVKRIHE YKRQLLNCLH VVTLYNRIKR DPAKAFVPRT VMIGGKAAPG YHMAKLIIKL VTSIGDVVNH DPVVGDRLKV IFLENYRVSL AEKVIPAADL SQQISTAGTE ASGTGNMKFM LNGALTIGTM DGANVEMAEE AGAENLFIFG LRVEDVEALD RKGYNAREYY DHLPELKQAV DQISSGFFSP KEPDCFKDIV NMLMHHDRFK VFADYEAYMQ CQAQVDQLYR NPKEWTKKVI RNIACSGKFS SDRTITEYAR EIWGVEPSDL QIPPPNIPRD

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 544-843 of human PYGB (NP_002853.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:20 - 1:100,IP,1:50 - 1:100

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PYGB

Target: PYGB (GPBB) (phosphorylase, Glycogen, Brain (GPBB))

Alternative Name: PYGB

Background: The protein encoded by this gene is a glycogen phosphorylase found predominantly in the brain. The encoded protein forms homodimers which can associate into homotetramers, the enzymatically active form of glycogen phosphorylase. The activity of this enzyme is positively regulated by AMP and negatively regulated by ATP, ADP, and glucose-6-phosphate. This enzyme catalyzes the rate-determining step in glycogen degradation.,PYGB,GPBB,Signal Transduction,Endocrine & Metabolism,Cardiovascular,Heart,Cardiac metabolism,PYGB

Molecular Weight: 96 kDa

Gene ID: 5834

UniProt: P11216

Pathways: Cellular Glucan Metabolic Process