QDPR antibody (AA 1-244)

Catalog No. ABIN6146531

This anti-QDPR antibody is a Rabbit Polyclonal antibody detecting QDPR in WB. Suitable for Human.

Quick Overview for QDPR antibody (AA 1-244) (ABIN6146531)

Target: QDPR (Quinoid Dihydropteridine Reductase (QDPR))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This QDPR antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-QDPR Antibody

Binding Specificity: AA 1-244

Sequence: MAAAAAAGEA RRVLVYGGRG ALGSRCVQAF RARNWWVASV DVVENEEASA SIIVKMTDSF TEQADQVTAE VGKLLGEEKV DAILCVAGGW AGGNAKSKSL FKNCDLMWKQ SIWTSTISSH LATKHLKEGG LLTLAGAKAA LDGTPGMIGY GMAKGAVHQL CQSLAGKNSG MPPGAAAIAV LPVTLDTPMN RKSMPEADFS SWTPLEFLVE TFHDWITGKN RPSSGSLIQV VTTEGRTELT PAYF

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-244 of human QDPR (NP_000311.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for QDPR

Target: QDPR (Quinoid Dihydropteridine Reductase (QDPR))

Alternative Name: QDPR

Background: This gene encodes the enzyme dihydropteridine reductase, which catalyzes the NADH-mediated reduction of quinonoid dihydrobiopterin. This enzyme is an essential component of the pterin-dependent aromatic amino acid hydroxylating systems. Mutations in this gene resulting in QDPR deficiency include aberrant splicing, amino acid substitutions, insertions, or premature terminations. Dihydropteridine reductase deficiency presents as atypical phenylketonuria due to insufficient production of biopterin, a cofactor for phenylalanine hydroxylase.,QDPR,DHPR,PKU2,SDR33C1,Cancer,Signal Transduction,Endocrine & Metabolism,Amino acid metabolism,QDPR

Molecular Weight: 22 kDa/25 kDa

Gene ID: 5860

UniProt: P09417