QDPR antibody

Catalog No. ABIN7252813

Product Details anti-QDPR Antibody

Target: QDPR (Quinoid Dihydropteridine Reductase (QDPR))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This QDPR antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Fusion protein of human QDPR

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.2 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for QDPR

Target: QDPR (Quinoid Dihydropteridine Reductase (QDPR))

Alternative Name: QDPR (QDPR Products)

Synonyms: DHPR antibody, PKU2 antibody, SDR33C1 antibody, 2610008L04Rik antibody, D5Ertd371e antibody, Dhpr antibody, QDPR antibody, qdpr antibody, MGC131372 antibody, DDBDRAFT_0168923 antibody, DDBDRAFT_0237752 antibody, DDB_0168923 antibody, DDB_0237752 antibody, CG4665 antibody, Dmel\\CG4665 antibody, si:ch211-89f22.2 antibody, quinoid dihydropteridine reductase antibody, quinoid dihydropteridine reductase S homeolog antibody, dihydropteridine reductase antibody, Dihydropteridine reductase antibody, bifunctional oxygen-insensitive NAD(P)H nitroreductase/dihydropteridine reductase NfnB antibody, quinoid dihydropteridine reductase a antibody, QDPR antibody, Qdpr antibody, qdpr antibody, qdpr.S antibody, Dhpr antibody, nfnB antibody, LOC5568428 antibody, dhpr antibody, qdpra antibody

Background: This gene encodes the enzyme dihydropteridine reductase, which catalyzes the NADH-mediated reduction of quinonoid dihydrobiopterin. This enzyme is an essential component of the pterin-dependent aromatic amino acid hydroxylating systems. Mutations in this gene resulting in QDPR deficiency include aberrant splicing, amino acid substitutions, insertions, or premature terminations. Dihydropteridine reductase deficiency presents as atypical phenylketonuria due to insufficient production of biopterin, a cofactor for phenylalanine hydroxylase.

Molecular Weight:

Observed_MW: Refer to figures

Calculated_MW: 26 kDa

UniProt: P09417