RAD23B antibody (AA 50-150)

Catalog No. ABIN6146632

The Rabbit Polyclonal anti-RAD23B antibody has been validated for WB, IHC and IF. It is suitable to detect RAD23B in samples from Human.

Quick Overview for RAD23B antibody (AA 50-150) (ABIN6146632)

Target: RAD23B (RAD23 Homolog B (RAD23B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAD23B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-RAD23B Antibody

Binding Specificity: AA 50-150

Sequence: GKILNDDTAL KEYKIDEKNF VVVMVTKPKA VSTPAPATTQ QSAPASTTAV TSSTTTTVAQ APTPVPALAP TSTPASITPA SATASSEPAP ASAAKQEKPA E

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 50-150 of human Rad23B (NP_002865.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:100 - 1:200,IF,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for RAD23B

Target: RAD23B (RAD23 Homolog B (RAD23B))

Alternative Name: RAD23B

Background: The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in the nucleotide excision repair (NER). This protein was found to be a component of the protein complex that specifically complements the NER defect of xeroderma pigmentosum group C (XP-c) cell extracts in vitro. This protein was also shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, and thus this protein may be involved in the ubiquitin mediated proteolytic pathway in cells. Alternative splicing results in multiple transcript variants encoding distinct isoforms.,RAD23B,HHR23B,HR23B,P58,Epigenetics & Nuclear Signaling,DNA Damage & Repair,RAD23B

Molecular Weight: 35 kDa/43 kDa

Gene ID: 5887

UniProt: P54727

Pathways: DNA Damage Repair