A2BP1 antibody (AA 1-130)

Catalog No. ABIN6146754

The Rabbit Polyclonal anti-A2BP1 antibody has been validated for WB and IHC. It is suitable to detect A2BP1 in samples from Human.

Quick Overview for A2BP1 antibody (AA 1-130) (ABIN6146754)

Target: A2BP1 (Ataxin 2-Binding Protein 1 (A2BP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This A2BP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-A2BP1 Antibody

Binding Specificity: AA 1-130

Sequence: MLASQGVLLH PYGVPMIVPA APYLPGLIQG NQEAAAAPDT MAQPYASAQF APPQNGIPAE YTAPHPHPAP EYTGQTTVPE HTLNLYPPAQ THSEQSPADT SAQTVSGTAT QTDDAAPTDG QPQTQPSENT

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human RBFOX1 (NP_665900.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:100 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for A2BP1

Target: A2BP1 (Ataxin 2-Binding Protein 1 (A2BP1))

Alternative Name: RBFOX1

Background: The Fox-1 family of RNA-binding proteins is evolutionarily conserved, and regulates tissue-specific alternative splicing in metazoa. Fox-1 recognizes a (U)GCAUG stretch in regulated exons or in flanking introns. The protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the product of the SCA2 gene which causes familial neurodegenerative diseases. Fox-1 and ataxin-2 are both localized in the trans-Golgi network. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.,RBFOX1,2BP1,A2BP1,FOX-1,FOX1,HRNBP1,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Neuroscience,Neurodegenerative Diseases,RBFOX1

Molecular Weight: 40 kDa/42 kDa/44 kDa

Gene ID: 54715

UniProt: Q9NWB1