RGS13 antibody (AA 1-159)

Catalog No. ABIN6146915

This Rabbit Polyclonal antibody specifically detects RGS13 in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for RGS13 antibody (AA 1-159) (ABIN6146915)

Target: RGS13 (Regulator of G-Protein Signaling 13 (RGS13))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RGS13 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-RGS13 Antibody

Binding Specificity: AA 1-159

Sequence: MSRRNCWICK MCRDESKRPP SNLTLEEVLQ WAQSFENLMA TKYGPVVYAA YLKMEHSDEN IQFWMACETY KKIASRWSRI SRAKKLYKIY IQPQSPREIN IDSSTRETII RNIQEPTETC FEEAQKIVYM HMERDSYPRF LKSEMYQKLL KTMQSNNSF

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-159 of human RGS13 (NP_002918.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:100 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for RGS13

Target: RGS13 (Regulator of G-Protein Signaling 13 (RGS13))

Alternative Name: RGS13

Background: The protein encoded by this gene is a member of the regulator of G protein signaling (RGS) family. RGS family members share similarity with S. cerevisiae SST2 and C. elegans egl-10 proteins, which contain a characteristic conserved RGS domain. RGS proteins accelerate GTPase activity of G protein alpha-subunits, thereby driving G protein into their inactive GDP-bound form, thus negatively regulating G protein signaling. RGS proteins have been implicated in the fine tuning of a variety of cellular events in response to G protein-coupled receptor activation. The biological function of this gene, however, is unknown. Two transcript variants encoding the same isoform exist.,RGS13,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,RGS13

Molecular Weight: 19 kDa

Gene ID: 6003

UniProt: O14921

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling