RIOK2 antibody (AA 253-552)

Catalog No. ABIN6146956

This Rabbit Polyclonal antibody specifically detects RIOK2 in WB. It exhibits reactivity toward Human.

Quick Overview for RIOK2 antibody (AA 253-552) (ABIN6146956)

Target: RIOK2 (RIO Kinase 2 (RIOK2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RIOK2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RIOK2 Antibody

Binding Specificity: AA 253-552

Sequence: TSHPNAEWYF DRDVKCIKDF FMKRFSYESE LFPTFKDIRR EDTLDVEVSA SGYTKEMQAD DELLHPLGPD DKNIETKEGS EFSFSDGEVA EKAEVYGSEN ESERNCLEES EGCYCRSSGD PEQIKEDSLS EESADARSFE MTEFNQALEE IKGQVVENNS VTEFSEEKNR TENYNRQDGQ RVQGGVPAGS DEYEDECPHL IALSSLNREF RPFRDEENVG AMNQYRTRTL SITSSGSAVS CSTIPPELVK QKVKRQLTKQ QKSAVRRRLQ KGEANIFTKQ RRENMQNIKS SLEAASFWGE

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 253-552 of human RIOK2 (NP_060813.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for RIOK2

Target: RIOK2 (RIO Kinase 2 (RIOK2))

Alternative Name: RIOK2

Background: Serine/threonine-protein kinase involved in the final steps of cytoplasmic maturation of the 40S ribosomal subunit. Involved in export of the 40S pre-ribosome particles (pre-40S from the nucleus to the cytoplasm. Its kinase activity is required for the release of NOB1, PNO1 and LTV1 from the late pre-40S and the processing of 18S-E pre-rRNA to the mature 18S rRNA. Regulates the timing of the metaphase-anaphase transition during mitotic progression, and its phosphorylation, most likely by PLK1, regulates this function.,RIOK2,RIO2,Signal Transduction,Kinase,RIOK2

Molecular Weight: 54 kDa/63 kDa

Gene ID: 55781

UniProt: Q9BVS4