Relaxin 2 antibody (AA 25-185)

Catalog No. ABIN6146976

This Rabbit Polyclonal antibody specifically detects Relaxin 2 in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for Relaxin 2 antibody (AA 25-185) (ABIN6146976)

Target: Relaxin 2 (RLN2)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Relaxin 2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Relaxin 2 Antibody

Binding Specificity: AA 25-185

Sequence: DSWMEEVIKL CGRELVRAQI AICGMSTWSK RSLSQEDAPQ TPRPVAEIVP SFINKDTETI NMMSEFVANL PQELKLTLSE MQPALPQLQQ HVPVLKDSSL LFEEFKKLIR NRQSEAADSS PSELKYLGLD THSRKKRQLY SALANKCCHV GCTKRSLARF C

Cross-Reactivity: Human, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 25-185 of human RLN2 (NP_604390.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Relaxin 2

Target: Relaxin 2 (RLN2)

Alternative Name: RLN2

Background: This gene encodes a member of the relaxin subfamily and insulin superfamily of peptide hormones. In humans there are three non-allelic relaxin genes. This gene encodes multiple protein isoforms, at least one of which undergoes proteolytic processing. This processing generates relaxin A and B chains that are linked by disulfide bonds to form the mature peptide hormone. This hormone plays a role in the male and female reproductive systems and was initially noted for its role in pregnancy. This protein also plays broader roles in the cardiovascular system, including in the regulation of blood pressure and control of heart rate, and data from animal models shows that this protein may have anti-fibrotic and cardioprotective effects.,RLN2,H2,H2-RLX,RLXH2,bA12D24.1.1,bA12D24.1.2,relaxin 2,RLN2

Molecular Weight: 12 kDa/21 kDa

Gene ID: 6019

UniProt: P04090

Pathways: Hormone Activity