RORC antibody (AA 120-320)

Catalog No. ABIN6147079

The Rabbit Polyclonal anti-RORC antibody (ABIN6147079) specifically detects RORC in WB. The antibody is reactive with Human samples.

Quick Overview for RORC antibody (AA 120-320) (ABIN6147079)

Target: RORC (RAR-Related Orphan Receptor C (RORC))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RORC antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RORC Antibody

Binding Specificity: AA 120-320

Sequence: KQLQQRQQQQ QEPVVKTPPA GAQGADTLTY TLGLPDGQLP LGSSPDLPEA SACPPGLLKA SGSGPSYSNN LAKAGLNGAS CHLEYSPERG KAEGRESFYS TGSQLTPDRC GLRFEEHRHP GLGELGQGPD SYGSPSFRST PEAPYASLTE IEHLVQSVCK SYRETCQLRL EDLLRQRSNI FSREEVTGYQ RKSMWEMWER C

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 120-320 of human RORC (NP_005051.2).

Isotype: IgG

Application Details

Application Notes: WB,1:1000 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for RORC

Target: RORC (RAR-Related Orphan Receptor C (RORC))

Alternative Name: RORC

Background: The protein encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known, however, studies of a similar gene in mice have shown that this gene may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2. Two transcript variants encoding different isoforms have been found for this gene.,RORC,IMD42,NR1F3,RORG,RZR-GAMMA,RZRG,TOR,Epigenetics & Nuclear Signaling,Transcription Factors,Nuclear Receptor Signaling,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,RORC

Molecular Weight: 55 kDa/58 kDa

Gene ID: 6097

UniProt: P51449

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway