SART3 antibody (AA 664-963)

Catalog No. ABIN6147392

The Rabbit Polyclonal anti-SART3 antibody is suitable to detect SART3 in samples from Human. It has been validated for WB and IHC.

Quick Overview for SART3 antibody (AA 664-963) (ABIN6147392)

Target: SART3 (Squamous Cell Carcinoma Antigen Recognized By T Cells 3 (SART3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SART3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-SART3 Antibody

Binding Specificity: AA 664-963

Sequence: AGPAGKCAAV DVEPPSKQKE KAASLKRDMP KVLHDSSKDS ITVFVSNLPY SMQEPDTKLR PLFEACGEVV QIRPIFSNRG DFRGYCYVEF KEEKSALQAL EMDRKSVEGR PMFVSPCVDK SKNPDFKVFR YSTSLEKHKL FISGLPFSCT KEELEEICKA HGTVKDLRLV TNRAGKPKGL AYVEYENESQ ASQAVMKMDG MTIKENIIKV AISNPPQRKV PEKPETRKAP GGPMLLPQTY GARGKGRTQL SLLPRALQRP SAAAPQAENG PAAAPAVAAP AATEAPKMSN ADFAKLFLRK

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 664-963 of human SART3 (NP_055521.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SART3

Target: SART3 (Squamous Cell Carcinoma Antigen Recognized By T Cells 3 (SART3))

Alternative Name: SART3

Background: The protein encoded by this gene is an RNA-binding nuclear protein that is a tumor-rejection antigen. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. This gene product is found to be an important cellular factor for HIV-1 gene expression and viral replication. It also associates transiently with U6 and U4/U6 snRNPs during the recycling phase of the spliceosome cycle. This encoded protein is thought to be involved in the regulation of mRNA splicing.,SART3,DSAP1,P100,RP11-13G14,TIP110,p110,p110(nrb),Epigenetics & Nuclear Signaling,RNA Binding,Cancer,Tumor biomarkers,SART3

Molecular Weight: 13 kDa/41 kDa/105 kDa/109 kDa

Gene ID: 9733

UniProt: Q15020

Pathways: Ribonucleoprotein Complex Subunit Organization