SETDB2 antibody (AA 1-280)

Catalog No. ABIN6147657

The Rabbit Polyclonal anti-SETDB2 antibody (ABIN6147657) specifically detects SETDB2 in WB and IF. The antibody is reactive with Human samples.

Quick Overview for SETDB2 antibody (AA 1-280) (ABIN6147657)

Target: SETDB2 (SET Domain, Bifurcated 2 (SETDB2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SETDB2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-SETDB2 Antibody

Binding Specificity: AA 1-280

Sequence: MGEKNGDAKT FWMELEDDGK VDFIFEQVQN VLQSLKQKIK DGSATNKEYI QAMILVNEAT IINSSTSIKD PMPVTQKEQE NKSNAFPSTS CENSFPEDCT FLTTENKEIL SLEDKVVDFR EKDSSSNLSY QSHDCSGACL MKMPLNLKGE NPLQLPIKCH FQRRHAKTNS HSSALHVSYK TPCGRSLRNV EEVFRYLLET ECNFLFTDNF SFNTYVQLAR NYPKQKEVVS DVDISNGVES VPISFCNEID SRKLPQFKYR KTVWPRAYNL TNFSSMFTDS

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human SETDB2 (NP_001153780.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SETDB2

Target: SETDB2 (SET Domain, Bifurcated 2 (SETDB2))

Alternative Name: SETDB2

Background: This gene encodes a member of a family of proteins that contain a methyl-CpG-binding domain (MBD) and a SET domain and function as histone methyltransferases. This protein is recruited to heterochromatin and plays a role in the regulation of chromosome segregation. This region is commonly deleted in chronic lymphocytic leukemia. Naturally-occuring readthrough transcription occurs from this gene to the downstream PHF11 (PHD finger protein 11) gene. Alternative splicing results in multiple transcript variants.,SETDB2,C13orf4,CLLD8,CLLL8,KMT1F,Epigenetics & Nuclear Signaling,Chromatin Modifying Enzymes,Methylation,SETDB2

Molecular Weight: 80 kDa/81 kDa

Gene ID: 83852

UniProt: Q96T68